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Reference Use of specific rRNA oligonucleotide probes for microscopic detection of Mycobacterium tuberculosis in culture and tissue specimens. St Amand AL, Frank DN, De Groote MA, Basaraba RJ, Orme IM, Pace NR. Journal of clinical microbiology. 2005.
Abstract Mycobacterium tuberculosis infections are a major global health problem. Fast and accurate detection of M. tuberculosis is clearly needed at both the clinical level and the research level. We report a rapid and reliable in situ hybridization technique using rRNA oligonucleotide probes for the identification of M. tuberculosis in tissues and cultures.
Pubmed ID 16208021